MEDICAL SOLUTION OF THE PROBLEM OF TREATMENT OF DIABETIC ULCERS THROUGH THE PRISM OF PHARMACEUTICAL DEVELOPMENT OF TOPICALLY ACTIVE DRUGS

Authors

  • L.O Prystupiuk Shupyk National Healthcare University of Ukraine, Pharmaceutical Technology and Biopharmaceuticals
  • L.L. Davtian Shupyk National Healthcare University of Ukraine, Pharmaceutical Technology and Biopharmaceuticals

DOI:

https://doi.org/10.30890/2709-2313.2023-25-00-013

Keywords:

diabetes, hydrogel, treatment of diabetic ulcers, topical medicine

Abstract

Diabetes is the most common non-infectious disease today. In 82% of all deaths in Ukraine, their cause is non-infectious diseases. The real number of patients with type 2 diabetes in most countries is higher than the official statistics. The number of pe

Metrics

PDF views
44
Jan 2024Jul 2024Jan 2025Jul 2025Jan 2026

References

Zimmet P.Z., Magliano D.J., Herman W.H., Shaw J.E. Diabetes: a 21st century challenge//Lancet. Diabetes and Endocrinology. –2013, December. – P.5-13]

International Diabetes Federation 2011. Global Burden: Prevalence and Projections,2011 and 2030. Available from http://www.diabetesatlas.org/content/diabetes-and-impairedglucose-tolerance

Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts.// Diabetes Care. – 2003. – V.26. – P.61–69

4 Основні причини високого рівня смертності в Україні, 2010; Диабет как независимый фактор риска преждевременной смерти, 2011; IDF Diabetes Atlas, sixth edition, 2013; Hansen L.J., Olivarius N de Fi, Siesma Velkert, 2009; Seshasai S.R.,Kaptoge S.R., Thompson A., 2011; Yang X., Co G.T. C., So W.Y., 2010

Alssema M., Vistisen D, Heymans M.W. et al DETECT-2 collaboration.The Evaluation of Screening and Early Detection Strategies for Type 2 Diabetes and Impaired Glucose Tolerance (DETECT-2) update of the Finnish diabetes risk score for prediction of incident type 2 diabetes.// Diabetologia. –2011 . –V.54. –№5. –Р.1004-1012. doi: 10.1007/s00125-010-1990-7. Epub 2010 Dec 12.

Engelgau M.M, Colagiuri S, Ramachandran A. et al. Prevention of type 2 diabetes: issues and strategies for identifying persons for interventions.//Diabetes Technol Ther. – 2004. – V.6. –P. 874–882.

Penn L, White M, Oldroyd J. et al Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UK.// BMC Public Health . –2009. –№9. –P.342.

Roumen C, Corpeleijn E, Feskens E.J. et al Impact of 3-year lifestyle intervention on postprandial glucose metabolism: the SLIM study.//Diabet Med. – 2008. –V. 25. –P. 597–605.

Knowler W.C, Barrett-Connor E, Fowler S.E. et al Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.// N Engl J Med . – 2002. – V. 346. – P. 393–403.

Li G., Zhang P. Wang J. et al. Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: a 23-year follow-up study.// Lancet Diabetes Endocrinol. – 2014 . –V.2. –№ 6. –Р. 474-480. doi: 10.1016/S2213-8587(14)70057-9.

Gillies C.L, Abrams K.R, Lambert P.C et al.Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis.//BMJ . –2007. –V.334. –P.299–308.

Dunbar J.A., Hernan A.L.,, Janus E.D. et al.Challenges of diabetes prevention in the real world: lesults and lessons from the Melbourne Diabetes Prevention Study.// BMJ Open Diabetes Res Care. – 2015 . –V. 3. – №1:e000131. doi: 10.1136/bmjdrc-2015-000131. eCollection 2015.

Simmons R.K, van den Donk M,Wareham N/J, Lauritzen T. Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.//Lancet. – 2011. –V.378. –P.156–167.

Christensen D.L, Witte D.R, Kaduka L. et al. Moving to an A1C-based diagnosis of diabetes has a different impact on prevalence in different ethnic groups.// Diabetes Care. – 2010. –V. 33. –P. 580–582.

Pani L.N, Korenda L, Meigs J.B. et al Effect of aging on A1C levels in individuals without diabetes:evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001–2004.// Diabetes Care. – 2008. –V. 31. –P. 1991–1996

World Health Organization (WHO) Consultation. Definition and diagnosis of diabetes and intermediate hyperglycaemia. 2006 http://www.who.int/diabetes/publications/Definition%20and%20diagnosis%20of%20diabetes_new.pdf.Diagnosis and classification of diabetes mellitus. Diabetes Care 2012;35 Suppl 1: S64-71.

Gillies C., Abrams K., Lambert P., 2007; Jeon C.V., Lokken R.P., Hu F.F., van Dam R.M., 2007

Age­ and sex­specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts// Diabetes Care. – 2003.V – 26. – P.61–69

Pani L.N., Korenda L., Meigs J.B. et al. Effect of aging on A1Cl levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001 – 2004 // Diabetes Care. – 2008. –V .31. – P.1991–1996

Iryna Vlasenko, Lena Davtian Study of the influence of armed conflict on the reimbursement of oral glucose lowering drugs in Ukraine // Pharmacia, 70(2): 275–281 DOI 10.3897/pharmacia.70.e99657

Study of pharmaceutical provision of type 2 diabetes therapy in Ukraine.IO Vlasenko, LL Davtian, ОM Zaliska - Pharmaceutical Review/Farmacevtičnij časopis, 2022 (2). – 12 - 20 (https://doi.org/10.11603/2312-0967.2022.2.13332)

Сучасні аспекти лікування ранового процесу із застосуванням покриттів (пов’язок) ОП Шматенко, ЛЛ Давтян, ТВ Приходько /Запорізький медичний журнал, 2022. - Vol. 24 No. 5 . – 599-606

Коритнюк РС, Загорій ГВ, Тарасенко ВО, Укадіке Ч. Технологія та фізикохімічна характеричтика гелів. Фармацевтичний журнал. 2012;3:38-42.

Орищенко, А. Ю. Гелі, як м’яка лікарська форма для зовнішнього застосування / А. Ю. Орищенко,Т. Г. Ярних, С. В. Олійник // Технологічні та біофармацевтичні аспекти створення лікарських препаратів різної направленості дії : матеріали VI Міжнар. наук.-практ. інтернет-конф., м. Харків, 11-12 листоп. 2021 р. - Харків : Вид-во НФаУ, 2021. - С. 408-410.

Гладышев В.В., Давтян Л.Л., Дроздов А.Л., Бирюк И.А., Кечин И.Л. Биофармация. Учебник для фармацевтических вузов и факультетов. 2-е изд. Под редакцией В.В. Гладышева. Днипро: ЧМП «Экономика». 2018.- 250 с

Декаметоксин і хлоргексидин на вітчизняному фармацевтичному ринку / Л. Л. Давтян, В. П. Попович, З. В. Малецька, Д. В. Рева // Фармацевтичний журнал. - 2014. - № 1. - С. 28-33. - Режим доступу: http://nbuv.gov.ua/UJRN/pharmazh_2014_1_4

Published

2023-12-30

How to Cite

Prystupiuk, L., & Davtian, L. (2023). MEDICAL SOLUTION OF THE PROBLEM OF TREATMENT OF DIABETIC ULCERS THROUGH THE PRISM OF PHARMACEUTICAL DEVELOPMENT OF TOPICALLY ACTIVE DRUGS. European Science, 3(sge25-03), 84–94. https://doi.org/10.30890/2709-2313.2023-25-00-013